Age Transformation Nov 1, 2009 | Age Transformation | Index Change Log

May 2007 | Wet & Dry Nov 1, 2009 | Chris Eve 2009 [Detail] Blemishes | March 1, 2010 | April 13, 2010 | May 14, 2010 | Aug 4, 2010 | Sept 3, 2010
Nov 29, 2010 | Jan 17, 2011 | Feb 28, 2011 | May Day, 2011 | July 5 2011 | Sept 11, 2011 | Nov 3, 2011 | Jan 10, 2012 | July 17, 2012 | Dec 31, 2012
March 5, 2013 | March 31, 2013 | May 1, 2013 | June 25, 2013 | July 31, 2013 | August 31, 2013 | Sept 30, 2013 | Oct 27, 2013 | Dec 2, 2013
Dec 31, 2013 | Jan 28, 2014 | Feb 28, 2014 | Mar 30, 2014 | May 8, 2014 | May 30, 2014 | July 31, 2014 | Aug 31, 2014 | Sept 20, 2014 | Nov 25, 2014
Jan 2, 2015 | Feb 2, 2015 | Mar 7, 2015

Masters of the elements are developing more effective methods based on both insight and experiment.
Left: Water Wet, Nov 1, 2009. Right: Bone Dry, Nov 6, 2009. It looks darker than this with hair oil.
Jim Green November 1, 2009, just out of the shower, Chronological Age = 60.465,
37.965 < Model Age < 40.455 after about 2.46 years of telomerase activation on the TA-65 scale.
Perhaps this is actually more like 45, so that we witness a 5.2 years per year rejuvenation rate
with our off-the shelf astragalus extract approach to telomerase activation. Hair is typically 50% grey at 50.

On the other hand, bone dry, my hair looks relatively grey. See photos of Sexy 60 Year Old Men,
including President Clinton, Harrison Ford, John Larroquette, Robert DeNiro, Sam Elliot and Martin Sheen & Jack Lemmon at 64.

By this time, it seems clear that I am getting results, although the actual rejuvenation speed involved has not been well-determined by expensive telomere length measurements. The model age times were obtained by assuming a rejuvenation rate between 8 and 9 years per year that I obtained from TA Sciences data on TA-65, which is based on processed astragalus extract, probably cycloastragenol taken 5 mg/day during activation periods.
Press for Einstein's Greying Rise Time.Press for Einstein's Greying Rise Time.
Above Left: Albert Einstein at 42 years of age wins the Nobel Prize in Physics.
Above Right: Greying Albert Eintein at 60 years of age writes Atom Bomb letter
to President Roosevelt with Leo Szilard advising FDR to proceed with the Manhattan Project.

Press for Jeanne Calment photo album.Press for Jeanne Calment photo album.
Left: Madame Jeanne Louise Calment, age 25.
Right: Madame Jeanne Louise Calment, age 60,
holding the record for aging at 122 years, 164 days.

I computed that I could probably get similar results by taking about $50 worth of astragalus extracts per month and including chitosan to improve the bioavailability of astragalosides in the astragalus extract, some of which should be converted to cycloastragenol by the digestive system before reaching the bloodstream. Telomerase activator treatment goes on for 15 days, followed by 15 days of telomerase inhibitor treatments with drugs like resveratrol, green tea extract, curcumin from turmeric, and silymarin. Throughout I take acetyl l-carnitine with alpha lipoic acid to combat mitochondrial aging, and CoQ10 as ubiquinol for lipofuscin removal. In addition every day I take 3000 mg of vitamin C, a super B-vitamin pill as a homocysteine screen featuring vitamin B-6, vitamin B-12, and folic acid, plus 400 x 4 IU of vitamin D3, and 500 mg of extra magnesium. Each day I get cocoa powder in water as a chilled drink and 5 grams of arginine with perhaps 500 mg of L-citrulline to improve my Nitric Oxide levels. To oppose lipid peroxidation, I take gamma tocopherol, usually from peanuts. I decided to emphasize whey protein as cottage cheese and skim milk, and to exercise daily to elevate my HGH and IGF-1 levels. I use minoxidil solution from Dillons to combat thinning hair. I have concluded astragaloside IV skin cream from Terraternal might be quite useful for hair restoration, as shown for telomerase activator application to the scalp at Artandi Labs, but so far astragaloside IV skin cream is not an off-the-shelf item here in Wichita.
The trend of things is toward something resembling the Twin Effect familiar from Special Relativity. After years in outer space soaring along at close to the speed of light, our hero returns to earth at 60+ to find his parent's generation completely wiped out by old age. However, he looks more like a man in his 40s most of the time, while many of his high school classmates from 1967 are quite white-haired. The face in the mirror after a shower begins to resemble the face of his son. It is, however, about what he expected. After a few more years, the difference should be even more visible, and our time-traveler hopes to penetrate all the way through to the 22nd century in this condition or better.
Age Transformation. Press for Highway 61 revisited: Green's 61st Birthday
Age Transformation: Model Age spread at the 58th, 60th, 61st, 62nd, 63rd, 64th, and 65th birthdays
in 2007, 2009, 2010, 2011, 2012, 2013 and 2014 starting with the 58th in 2007,
using deaging lines for TA-41 (not TA-65) rejuvenation rates of B = -8 and B = -9 years per year,
plus better astragalus extract model ages with B = -5.2. All dates are computed for May Day,
since treatment started on May 1, 2007 in advance of my birthday on May 13.

Δt = 6.3 years to Model Age 25.11, Calendar Age = 64.3 on August 31, 2013
on the rightmost Astragalus Extract line, about what was observed.

When I was 60, restaurant help guessed my age at 40, but my hair was oiled.
The drawing seems to mythically be one of Superman's crystals from the Fortress of Solitude.
Elders contemplate predictive crystal visions at the end of time. You must have been a beautiful baby, but baby, look at you now.

Deaging Plot Corresponding to Astragalus Extract Observations after about 2.5 years.
(From 58 to Model Age 45 at 60.5 in 2.5 years, projected to Model Age 25 at 64 in 6.34 years from 58.)
The observed rejuvenation rate is perhaps B= -5.2 years per year, corresponding to the top line on the chart. At the present time, I may seem to be 45, so that at this rate I would achieve a 25 year old appearance at about 64.35 years of age in 2013. The dotted lines are for TA-65 at -8 and -9 years per year. Basic cost is about $55/month, including Chitosan, or $660/year, yielding $4,188 for 6.34 years to 25 at 64. Extra money might be spent on CoQ10, alpha lipoic acid with acetyl L-carnitine, magnesium, zinc, vitamin D, multiple vitamins, resveratrol for the off part of the cycle, and other refinements.

It seems likely that deaging with astragalus was discovered in the past, but rarely witnessed because of the expense of implementing treatment and the lack of a conceptual model featuring the gradual regrowth of a clocking molecule controlling cellular replicative senescence and associated old age side effects. DNA repair in animals very subject to predation is generally poor, so that the animal perishes of mitochondrial aging problems, rather than of problems with its nuclear DNA. Lives not worth living because of external predation are terminated by something other than limitations imposed by replicative senescence. Rodent telomeres are long enough for 6 standard rat lifetimes, while bats, little subject to predators, live into their forties. In the human species, life span is primarily limited by diseases associated with replicative senescence and telomeric DNA repair. Atherosclerosis appears in old age when the vascular endothelial cells have become senescent and more adhesive to monocytes. Men die then from heart attack, stroke, and cardiovascular disease. Carcinomas appear when the cellular environment allows telomeric crisis to occur, such that chromosomes fuse at their endpoints when telomeres have become disasterously short, shrinking beyond the first stop point associated with senescent cell cycle arrest. Similarly, the microglial cells derived from hematopoetic stem cells that clean up brain debris become senescent, allowing inflammation to occur leading to Alzheimer's Disease and other disorders associated with dementia. With controlled telomerase activation to repair and re-extend telomeric DNA, these effects can be eliminated. Careful attention to all factors involved in aging may now be capable of eliminating or vastly reducing human death from old age. At the End of Evolution, our external machinery and mental apparatus continued to develop, now evolving advanced limbs in the form of automobiles, airplanes, and spacecraft, while our expanding insight into molecular biology and medicine began to turn our bodies into life extended forms subject primarily to accidents, storms, and wars and much less to diseases of old age. In the future, evolution will be more carefully managed and differently driven.
- Jim Green, November 1, 2009.

Press for Calendar Age 63.88
Anti-Aging Flight Plan (reminiscent of My World Line by George Gamow). Δt = 6.3 years.
Here Model_Age = Bt + Starting_Age, B=1 for normal aging, B > 1 for accelerated aging,
B=0 for no aging, and B < 0 for rejuvenation, or negative aging. Here initially B= 1 for
normal aging, then B= - 5.2 years/ year during the deaging phase, followed by B=0 zero aging
until Madame Jean Louise Calment's 122 years, 164 days record is exceeded at 2071.9634 AD,
which should be right at the Winter Solstice when shadows are shortest about Dec 22, 2071.
About this time the S.Monocerotis skywalker above the Cone Nebula crosses the meridian.

Note the "Cross of Years" formed by the 110 and 122.45 barriers. There are thousands
of Americans over 100, of whom hardly any will get though the 110 year barrier without medicine.

Press for Orion in celestial sphere context.
Although Superman did not always seem to have great business sense, he did show great largess.


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May 2007 | Wet & Dry Nov 1, 2009 | Chris Eve 2009 [Detail] Blemishes | Mar 1, 2010 | April 13, 2010 | May 14, 2010 | Aug 4, 2010 | Sept 3, 2010
Nov 29, 2010 | Jan 17, 2011 | Feb 28, 2011 | May Day, 2011 | July 5 2011 | Sept 11, 2011 | Nov 3, 2011 | Jan 10, 2012 | July 17, 2012 | Dec 31, 2012
March 5, 2013 | March 31, 2013 | May 1, 2013 | June 25, 2013 | July 31, 2013 | August 31, 2013 | Sept 30, 2013 | Oct 27, 2013 | Dec 2, 2013
Dec 31, 2013 | Jan 28, 2014 | Feb 28, 2014 | Mar 30, 2014 | May 8, 2014 | May 30, 2014 | July 31, 2014 | Aug 31, 2014 | Sept 20, 2014 | Nov 25, 2014
Jan 2, 2015 | Feb 2, 2015 | Mar 7, 2015

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Music[2] || Email[2]: JimGreenHimself@gmail.com. Thanks for sending your pointers, insights, and remarks.