May Day, 2011 Pics at the 4th year of my Experiment
| Age Transformation
| Index Change Log|
Longevity: James A. Green, born 5/13/49. |
Cyclic Treatment Time Machine Model |
The Time Machine (1960) from George Pal.
| Wet & Dry Nov 1, 2009
| Chris Eve 2009
| March 1, 2010
| April 13, 2010
| May 14, 2010
| August 4, 2010
| Sept 3, 2010
Nov 29, 2010
| Jan 17, 2011
| Feb 28, 2011
| May 1, 2011
| July 5, 2011
| Sept 11, 2011
| Nov 3, 2011
| Jan 10, 2012
| July 17, 2012
| Dec 31, 2012
March 5, 2013
| March 31, 2013
| May 1, 2013
| June 25, 2013
| July 31, 2013
| August 31, 2013
| Sept 30, 2013
| Oct 27, 2013
| Dec 2, 2013
Dec 31, 2013
| Jan 28, 2014
| Feb 28, 2014
| Mar 30, 2014
| May 8, 2014
| May 30, 2014
| July 31, 2014
| Aug 31, 2014
| Sept 20, 2014
| Nov 25, 2014
Jan 2, 2015
| Feb 2, 2015
| Mar 7, 2015
Left: May Day, 2011, By the fireplace at Calendar Age: 61.964, Model Age: 37.22, haunted by the ghost of
My father James A. Green Jr. (1920-1983)
at 38 with our family dog Puddles in 1958.
Perhaps he was greyer at 38 than I am
at Calendar Age 61.964,
Model age 37.22.
Rejuvenation rate B = - 5.1 years/year. (See Age Transformation.) Next: Sheds 15 pounds to loose 15 years.
Right: My father James A. Green Jr. in 1958 at 38 years of age with
the family grape-taster Puddles.
"In normal aging, the onset of hair graying
occurs at 34+-9.6 years of age in Caucasians
and 43.9+-10.3 years in African Americans, a period in which hair follicles pass
though approximately 7-15 complete hair cycles." - Kavita Y. Sarin and
Steven E. Artandi
and Loss of Melanocyte Stem Cells
Stem Cell Review
see E. Wang, MK Artandi, AE Oro, SE Artandi (2005),
telomerase induction causes proliferation of hair follicle stem cells
436, 1048-1052. See also Siegl-Cachedenier I, Flores I, Klatt P, Blasco MA,
reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with
critically short telomeres
J Cell Biol
2007 Oct 22;179(2):277-90.
Right: Before Shaving on May 8, 2011. In front of a dinette PC.
Left: Hair on May Day, 2011. My 62nd birthday is May 13, 2011.
Opening the Telomere T-Loop to Improve Telomerase Access
The last few days I've been experimenting with elevating
extract after an exercise session
just before bedtime while dosed with several other
. The high
sweeps sugar out of the blood after a workout, producing a tired,
and eventually hungry feeling from
you would not want to suffer while exercising.
It helps you go to sleep
after a workout, however, and Fenugreek
helps with both
to the telomere
also restoring muscle tissue glycogen
I used 10 grams of L-arginine
to elevate nitric oxide
which activates telomerase in vascular
endothelial cells, along with 2 grams of
The combination of L-arginine
increases expression of HGH
which is telomerase-activating. In addition, I took sweetened
tea to elevate
Nerve Growth Factor
which elevates the expression of
helix-loop-helix transcription factor
which acts on the hTERT
promote the transcription of
component of telomerase
In addition, I took a big dose
of astragalus extract
amounting to perhaps 10 or 15 mg of astragalosides
and rubbed in roughly
10 mg of cycloastragenol
. I also took Forskolin
before the workout to elevate
which has telomerase-elevating effect in heart muscle tissues, skeletal muscles, and
melanocytes that color hair. The Fenugreek
extract elevates testosterone
after the workout, and also
telomerase activation by promoting the expression of the transcription factor HIF-1
together with 4-hydroxyisoleucine
that elevates insulin
phosphorylate tankyrase 1
which opens telomere t-loops
to access by
the telomerase holoenzyme
. I had
also taken 2-3 grams of niacinamide
), which provides a
substrate for the
reaction that strips telomere t-loop
closure protein TRF1
from the telomere, allowing it to open for
access by telomerase.
I am not rubbing Fenugreek
alcohol extract over my chest,
which would produce the breasted look within 8 weeks.
I wonder if such an extract with its Fenugreek saponins
might not be useful for the scalp and hair follicles. Just taking Fenugreek
extract orally before bedtime does not typically produce a breasted transformation in 2 weeks,
and I propose to try cycling Fenugreek
with my telomerase activators
(2 weeks on, then 2 weeks telomerase inhibitors
in order to
improve the bioavailability of telomerase at the telomere
for my rejuvenation application. It takes 4-8 weeks to produce breast enlargement in women
at a dose of about 3 grams of Fenugreek
which costs < $9 per pound. However, this is preceeded by a tingly feeling,
so that you can detect when it is starting to impact cellular differentiation in tissue and quit. The
tends to boost appetite, and is used to fatten up
farm animals. High insulin can make you feel apple-cheeked by socking blood sugar into your cheeks, which I am
trying to compensate for by using more fiber during the day and less meat and fish.
Dame Elizabeth Taylor was in great shape at 60 for a
over at 60 photo.
She was interested in Life Extension research,
and would have gladly served as the new Jeanne Calment
Liz Taylor Wins with Life Extension Technique and
Anti-Aging Makeup Expertise,
With grandfather James A. Green Sr.
(1890-1973), shown at age 59 in 1949.
Haunting with Electric Clarity from the 5th dimension in etherial movie frames,
LOOking like the Cat's Meow I'd rather have heard. Study, then ride heady pills into the future.
Me and Julio Down by Schoolyard by
Paul Simon or
A Summer Song by
Chad & Jeremy.
The Pretty Little Surey with The Fringe on the Top - An old favorite of my Grandfather Green.
April 2011 Life Extension Program with New Insights for May
Cycloastragenol and Astragalus Extract for Primary Telomerase Activation
In April 2011 I used experimenter's
(10 mg/day) from a chemical supply company
for the rejuvenation application for
the first 15 days of the month, plus a couple of bottles of
astragalus root extract
1 mg astragalosides
per 30 drops),
which I applied to my scalp. I tried to put the cycloastragenol in via a transdermal
route of application scheme.
Forskolin for Hair Darkening Improvements
I started taking Forskolin
to darken my hair toward the end of the month,
after I read that Forskolin
darkens hair, and upgraded my
index entry on the topic.
Thymic Restoration with Telomerase Activation from Nitric Oxide
This April 2011 I used 10 grams of arginine
per day during the
first 15 days of the month in order to stimulate the
restore youthful levels of
endothelial progenitor cells
Confining High Vitamin D to Telomerase Inhibition Periods
Otherwise, I followed the routine from the prior month,
except that I used high vitamin D
levels only during the final
15-day telomerase inhibition periods
as I confirmed in February that Vitamin D3
Nicotinamide to Impove the Hayflick Limit
I tried again to follow Kang's advice on nicotinamide
which has extended life spans
of cells in the lab by a factor of 1.6. (See Kang HT, Lee HI, Hwang ES (2006),
replicative lifespan of Human Cells
, 5(5): 423-36.)
This is due to fewer
telomeric repeats lost per cell division
so that cells can divide more. This month I could obtain 500 mg capsules of
a form of niacin
, also a form of
which I added to my usual 4 daily
Super B-Complex pills
including 100 mg of niacinamide
, also called
], in addition to
and material functioning like a
I took the nicotinamide
recommended by Kang, 500 mg in the morning and 500 mg before bedtime.
Nicotinamide to Increase Tankyrase Expression and NAD+ levels for opening T-Loops
I note that my recent research shows that niacinamide
can be taken < 3 grams/day (while taking
a telomerase activator
to provide the NAD+ substrate
required by tankyrase 1
to strip TRF1 telomere binding protein
opening telomere loops
for telomerase access and subsequent extension of the telomere. Alternatively,
taken directly as a supplement to enhance TRF1 t-loop closure protein stripping.
Furthermore, insulin boosters
can be used at the end of a workout to
phosphorylate tankyrase 1
making it active for this reaction. Furthermore,
tankyrase 1 expression
is known to be enhanced by niacinamide
so that in May for the first time I will be consciously opening telomere loops with tankyrase 1 before
acting on them with telomerase expressed via the upregulation of hTERT mRNA levels using small
molecule telomerase activators.
Boosting HGH levels for growth hormone telomerase activation
used whey protein
up as high as possible
to get higher hTERT
mRNA levels to
support telomerase activity (7)
. However, unless I get behind heavier iron,
nothing much will happen to my physical size from doing pushups, curls with light dumbells, and
other light exercise, although my HGH
levels are high.
I had to do 35 pull-ups with 100 lb chained on to get 19 inch arms back when I was
really doing some bodybuilding
could usually get me through sticking points, which is how I pressed 300 lb at 48.
, however, ought to eventually produce a leaner, more
photogenic look. I don't know why I find
such a devilish challenge.
Telomerase Activation On Period (1st 15 days of the month)
10 mg/day Cycloastragenol
(10 mg in skin cream at bedtime),
____[but preferably 25 mg of cycloastragenol or TA-65 orally]),
4 mg astragalosides
/day to the scalp as a
____GAIA Herbs Astragalus
, 30 drops per 1 mg astragalosides
10 grams arginine
as an HGH
secretagogue and telomerase activator via
, including Rosemary tea (extract) and
Essential Oil of Rosemary
< 3 grams (Now Foods), to enable
____and improve the Hayflick cell division limit
(Kang, et al, 2006
for telomerase activation
heart stem cells, muscle stem cells, and hair folicle melanocytes.
(tuna, skim milk, grapefruit, pineapple).
Every Day of the Month
1 or 2 Equate multivitamin pills
3000 mg of vitamin C
500 mg per serving, distributed over the day.
500 mg x 2 of Nicotinamide (Niacinamide)
(Now Foods niacinamide
100 mg Qunol
/day (a Wal-Mart brand claiming x 3 bioavailability
4 x (200 mg alpha lipoic acid
+ 400 mg
4 x Acetyl L-Carnitine
____4 x (150 mg vitamin C
100 mg vitamin B1
20 mg vitamin B2
25 mg niacinamide
____2 mg vitamin B6
400 mcg Folic Acid
15 mcg vitamin B12
, 3.8 mcg
____5 mg Pantothenic acid
4 x 400 mg Magnesium
, with 15 mg
(15 mcg vitamin B12
, 3.8 mcg
Telomerase Inhibition Period (Last 15 days of the month)
4 x 2000 IU, vitamin D3
, Super Strength, Spring Valley
every day to the scalp as a
inhibitor, foils hair loss.
3 x 2 tablespoons Coca
powder in ice water, taken like tea.
4 x Green Tea
apple cider vinegar
8 x 200 mg Red Wine Complex
), Spring Valley.
4 x 1000 mg Omega-3
, Spring Valley.
1 x 3 mg Melatonin
(Spring Valley Tablet) at bedtime.
, taken in water with black pepper to improve
(tends to generate anticancer
Left Jim Green (58), May 2007.
Right Jim Green (61.964, Model Age: 37.22), May 1, 2011.
Old Side Story: Still a little too heavy to be as photogenic as possible.
I look my best when I'm crystalline-lean.
[Previous | Next]
Left Albert Einstein, age 26.
Right Albert Einstein at age 62 plays violin.
Einstein passed away at 76 in 1955, igniting a dramatic radio report I heard as a child.
See Einstein's Greying Rise Time.
Above: J. Robert Oppenheimer
[April 22, 1904 - February 18, 1967 (aged 62)].
Anti-Aging Flight Plan down to Model Age 25.12 on August 31, 2013 at Age 64.3.
Here Model_Age = Bt + Starting_Age, B=1 for normal aging, B > 1 for accelerated aging,
B=0 for no aging, and B < 0 for rejuvenation, or negative aging. Here initially B= 1 for
normal aging, then B= - 5.2 years/ year during the deaging phase, followed by B=0 zero aging
until Madame Jean Louise Calment's 122 years, 164 days record is exceeded at 2071.9634 AD,
which should be right at the Winter Solstice when shadows are shortest about Dec 22, 2071.
About this time the S.Monocerotis skywalker
above the Cone Nebula crosses the meridian.
Note the "Cross of Years" formed by the 110 and 122.45 barriers. There are thousands
of Americans over 100, of whom hardly any will get though the 110 year barrier without medicine.
Music: Silver Thunderbird
and Walking in Memphis by Marc Cohn.
"If the radiance of a thousand suns
Were to burst at once into the sky,
That would be like the splendor
Of the Enlightened One..."
- from The Bagavid Gita, also quoted by J. Robert Oppenheimer.